2014.09.23 | Research news

Torben Heick Jensen has been joined as a member of the Board of Reviewing Editors at the online journal eLife

eLife is a peer-reviewed open access scientific journal for the biomedical and life sciences. It was sponsored by the Howard Hughes Medical Institute, Max Planck Society and Wellcome Trust following a workshop held in 2010 at the Janelia Farm Research Campus and finally established at the end of 2012.

2013.11.24 | Research news

Proteins suppress useless gene activity in human cells

A new study shows how our cells sort the wheat from the chaff in a tangle of useful and useless gene molecules. In collaboration with international research groups, a Danish research team from Aarhus University has now found a mechanism that helps the cells prevent accumulation of the many useless RNA molecules being constantly produced by runaway…

2013.09.27 | Research news

Torben Heick Jensen awarded ERC Advanced Grant

The European Research Council (ERC) has awarded an Advanced Grant to Professor Torben Heick Jensen to support his research into genome expression, stability and technology.

2013.07.14 | Research news

How human gene promoters become directional

An international research team has disclosed how cellular gene transcription and RNA degradation processes collaborate to achieve a directional output from human genes.


The regulation and fidelity of gene expression is of paramount importance for the maintenance and differentiation of all living organisms. While attention historically has been focused on the process of gene activation (transcription), the past two decades have highlighted an equally important contribution to gene regulation at the post-transcriptional level. The Centre for mRNP Biogenesis and Metabolism studies the crosstalk between transcriptional and post-transcriptional processes, which establishes a network of interdependencies that ultimately regulate gene expression. Our focus is on structure/function relationships of mRNP formation and its quality control as well as the occurrence, and putative function, of non-coding RNA transcription.

So far our efforts have led to several important discoveries, including:

  • yeast cryptic unstable transcripts (CUTs) and human promoter upstream transcripts (PROMPTs)

  • the elucidation of regulatory principles for mRNP quality control in the nucleus and the cytoplasm

  • the "reverse" cross-talk between mRNA processing and transcription

  • key structures of RNP factors and complexes

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Revised 2014.09.23

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